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Korea scientist found carcinogenic mechanism by FH defect

Published: 2005-09-12 07:00:00
Updated: 2005-09-12 07:00:00
Prof. Chung Yeong-jin of Busan National Univ. College of Pharmacy reported his study on the August edition of a world medical journal "Cancer Cell" about a molecular level of the carcinogenic mechanism by an FH (fumarate hydratase) genetic mutation. FH is an enzyme involved in the TCA cycle at the cell mitochondria.

His finding reveals that the defect of FH increases HIF-1, which blocks HP...

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